Yehya N, et al. - Authors ascertained if clinical characteristics and predictors of mortality differed between direct and indirect acute respiratory distress syndrome (ARDS), and separately between infectious and non-infectious ARDS. Distinct clinical characteristics, but similar outcomes and similar predictors of mortality of direct and indirect ARDS were noted in children. On the contrary, heterogeneity of clinical characteristics, mortality, and predictors of mortality was demonstrated by infectious and non-infectious ARDS, with traditional predictors of ARDS mortality only applicable to infectious ARDS.