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Substantial weight gain in adulthood is associated with lower probability of live birth following assisted reproduction

The Journal of Nutrition Jan 19, 2021

Gaskins AJ, Arvizu M, Mínguez-Alarcón L, et al. - Researchers aimed at evaluating if and how female BMI (in kg/m2) at 18 y and weight change from 18 y to current age associate with assisted reproduction technology (ART) outcomes. They performed a prospective cohort study of 486 women who underwent 863 ART cycles at the Massachusetts General Hospital Fertility Center (2004–2018). Median (range) BMI of 20.6 (14.8 to 36.4) at 18 y and 23.3 (16.1 to 45.8) at study entry were reported in these women. Observations suggest a negative correlation of weight gain in adulthood with ART success, particularly among women who were heavier at 18 y. These data served as an addition to the growing literature favoring the benefits of preventing weight gain in adulthood on female fertility.

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