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Suboptimal biochemical riboflavin status is associated with lower hemoglobin and higher rates of anemia in a sample of Canadian and Malaysian women of reproductive age

The Journal of Nutrition Aug 09, 2019

Aljaadi AM, How RE, Loh SP, et al. - Among healthy women 19-45 years old who are not pregnant and not breastfeeding living in Vancouver, Canada (n = 206), and Kuala Lumpur, Malaysia (n = 210), researchers evaluated the biomarker status of riboflavin and its relation to hemoglobin levels and anemia. In fasting blood samples, they evaluated riboflavin status, hematological indicators, soluble transferrin receptor, ferritin, vitamin A, folate, and vitamin B-12 levels. Canadian and Malaysian women were found to have biochemical riboflavin deficiency; Malaysian women had higher rates of deficiency. For forecasting hemoglobin and anemia, deficient biomarker status of riboflavin was identified as a weak but significant predictor. This is indicative of a potentially small protective role of riboflavin deficiency correction in anemia.

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