Broughton ST, Ahmad M, Soliman EZ, et al. - Whether subclinical myocardial injury (SCMI) prevalence as well as link with mortality vary by race, categorized as non‐Hispanic White (White), non‐Hispanic Black (Black), and Mexican American, was determined herein among 5,852 participants from the National Health and Nutrition Examination Survey (NHANES III, 1988–94). The study sample with age 58.5 ± 13.2 years comprised 54% women, 52% Whites, 23% Blacks, and 25% Mexican Americans. Participants were free of cardiovascular disease at the time of enrollment. The prevalence of SCMI was estimated to be 23.4%, 21.8%, and 18.0%, in Whites, Blacks, and in Mexican Americans, respectively. Findings revealed a lower prevalence of SCMI but elevated risk of cardiovascular mortality in Mexican Americans. Screening for SCMI may not only detect people carrying an elevated risk but also may enhance targeted prevention efforts.