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Subanesthetic ketamine infusions for the management of pediatric pain in non-critical care settings: An observational analysis

Acta Anaesthesiologica Scandinavica Jul 23, 2019

Masaracchia MM, et al. - In this retrospective study, researchers focused on the practice of employing ketamine for pediatric pain management in non-critical care settings. For this purpose, they analyzed patients aged 0-21 years taking low-dose ketamine infusions (≤0.3 mg/kg/hour) in inpatient care units over five years. A total of 270 subhypnotic ketamine infusions were received by approximately 172 patients. Mean verbal pain scores, before and after ketamine use, showed significant reductions, though opioid consumption was similar. Based on the findings, the effective use of ketamine as a component of a multimodal analgesic regimen in pediatric patients in non-critical care settings is supported in this study. An acceptable side effect profile, with no attributable escalations in care or serious adverse events, was also reported.
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