Study of small intestinal bacterial overgrowth in a cohort of patients with abdominal symptoms who underwent bariatric surgery
Obesity Surgery Feb 15, 2020
Mouillot T, Rhyman N, Gauthier C, et al. - As small intestinal bacterial overgrowth (SIBO) is a common complication of bariatric surgery and there is variation in digestive decontamination treatments with oral antibiotic therapy, researchers sought to ascertain the characteristics of bariatric surgery patients who underwent a glucose breath test (GBT) and investigated the effectiveness of the antibiotic decontamination therapy. In this retrospective study, they included 101 operated patients [Roux-en-Y bypass (RYB), omega bypass and sleeve gastrectomy] who underwent a GBT (75 g/250 mL). The participants comprised 85 women and 16 men (48.5 ± 3.6 years old). Based on outcomes, they recommend systematically considering SIBO in the context of abdominal symptoms in bariatric surgery patients, regardless of the type of surgery, especially in cases who are older or female and after proton pump inhibitor treatment. Gentamycin/metronidazole and metronidazole treatments appeared similar regarding digestive decontamination.
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