Structure-function relationships in glaucoma using enhanced depth imaging optical coherence tomography-derived parameters: A cross-sectional observational study
BMC Ophthalmology Feb 21, 2019
Lopes FS, et al. - Using enhanced depth imaging spectral-domain optical coherence tomography (EDI OCT)-derived parameters, investigators examined 73 eyes to assess the structural and functional correlations in subjects with glaucoma. They observed significant differences between the different stages of glaucoma with average Bruch’s membrane opening (BMO)-minimum rim width (BMO-MRW) (an EDI OCT parameter). They also noted vital structure-function relationships between visual field (VF) index (VFI) values and prelaminar neural tissue area, average BMO-MRW, superior BMO-MRW, and inferior BMO-MRW. Overall, they recorded better outcomes for neural tissue-based indexes in comparison to LC-derived parameters.
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