Structure–function relationship between Bruch’s membrane opening-minimum rim width and perimetry in open-angle glaucoma subtypes
Graefe's Archive for Clinical and Experimental Ophthalmology Dec 17, 2019
Li R, Wang X, Wei Y, et al. - A total of 83 healthy and 106 glaucoma individuals [49 with primary open-angle glaucoma (POAG) and 57 with normal-tension glaucoma (NTG)] were enrolled and underwent optical coherence tomography (OCT), Bruch’s membrane opening-minimum rim width (BMO-MRW) scans, and Humphrey visual field (VF) analyzer examination in order to explore the threshold value of BMO-MRW where VF damage happens in OAG and examine whether there were structural variations between POAG and NTG. In OAG, BMO-MRW loss appeared to occur prior to the onset of perimetric impairment. Moreover, in comparison with POAG, NTG seemed to have more critical rim damage, particularly in the inferotemporal quadrant at the onset of discoverable VF defects.
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