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Structural durability of early-generation transcatheter aortic valve replacement valves compared with surgical aortic valve replacement valves in heart valve surgery: A systematic review and meta-analysis

Journal of Cardiothoracic Surgery Jun 11, 2020

Ler A, Ying YJ, Sazzad F, et al. - Aortic stenosis are currently managed with open surgical aortic valve replacement (SAVR) as well as with endovascular transcatheter aortic valve replacement (TAVR). Researchers here examined the 1-year, 2–3 year and 5-year structural durability of TAVR valves vs that of SAVR valves. Performing a systematic literature search in July 2019 on Medline (via PubMed), Embase and Cochrane electronic databases according to the PRISMA guidelines, they identified 13 randomized controlled trials for inclusion in the meta-analysis. Per outcomes, structural valve deterioration seems to occur more frequently in TAVR valves and thus these are potentially less structurally durable than SAVR valves, given the link of TAVR valves with higher rates of moderate or severe aortic regurgitation, paravalvular regurgitation and reintervention in the 1-year-, 2–3 year, and 5-year period.

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