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Structural changes of cerebellum and brainstem in migraine without aura

The Journal of Headache and Pain Sep 07, 2019

Qin Z, He XW, Zhang J, et al. - Researchers investigated cerebellar and brainstem structural changes associated with migraineurs via performing assessment of voxel-based morphometry (50 controls, 50 migraineurs without aura [MWoAs]) and diffusion tensor imaging (46 controls, 46 MWoAs). The cerebellum and the local brainstem in MWoAs showed microstructural changes. Findings suggested a possible contribution of these structural differences to dysfunction of the transmission and modulation of noxious information, trigeminal nociception, and conduction and integration of multimodal information in MWoAs. Overall, findings indicated that the cerebellum and the brainstem may be involved in the pathology of MWoAs.

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