Erben V, et al. - In this cross-sectional analysis, researchers examined the link between a healthy lifestyle pattern and the prevalence of early and advanced colorectal neoplasms in 13,600 participants of screening colonoscopy in Saarland/Germany (mean age 62.9 years) who were enrolled in the KolosSal study from 2005 until 2013. They used multiple logistic regression analyses with comprehensive adjustment for potential confounders, to determine the association of an a priori defined healthy lifestyle score—including dietary intake, alcohol consumption, physical activity, smoking and body mass index (BMI)—with early and advanced colorectal neoplasms. According to findings, a healthy lifestyle was strongly related to lower risk of all stages of colorectal neoplasms. They observed robust inverse dose–response associations between an overall healthier lifestyle pattern and presence of advanced colorectal neoplasms, nonadvanced adenomas and hyperplastic polyps. For the highest vs the lowest category of the healthy lifestyle score, the adjusted odds ratios (95% CI) of 0.41 (0.30–0.56), 0.42 (0.33–0.54) and 0.39 (0.29–0.54) respectively, was estimated.