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Statin use and pneumonia risk in Parkinson disease

Parkinsonism & Related Disorders Oct 02, 2021

Yun SJ, Byun SJ, Kim HJ, et al. - Parkinson disease (PD) patients exhibited a lower risk of pneumonia in relation to statin use. Statins might influence the occurrence of pneumonia by decreasing cholesterol or slowing the progression of PD as neuroprotective agents.

  • Using the 2002-2017 National Health Insurance Service database, PD patients who had received statins and developed pneumonia during observation were included.

  • The self-controlled case series analysis involved 337 of 10,159 patients with PD.

  • The statin-exposed period showed reduced incidence of pneumonia vs unexposed period (incidence rate ratio, 0.88; 95% CI, 0.86-0.91).

  • Statin use was associated with a significantly decreased risk of developing pneumonia (adjusted hazard ratio, 0.69; 95% CI, 0.62-0.78).

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