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Statin use and breast cancer survival – A Swedish nationwide study

BMC Cancer Jan 17, 2019

Borgquist S, et al. - Considering the sizeable body of evidence suggesting statins as capable of ceasing breast cancer progression and preventing breast cancer recurrence, researchers undertook this considerably sized study investigating the association between both pre- and post-diagnostic statin use and breast cancer outcome. During a median follow-up time of 61.6 months in this Swedish nation-wide retrospective cohort study of 20,559 Swedish women diagnosed with breast cancer (July 1st, 2005 through 2008), 4678 deaths were reported. Of these 2669 were considered breast cancer related deaths. Regular pre-diagnostic statin use was noted to be associated with lower risk of breast cancer related deaths when compared to non- or irregular statin use. Findings thereby suggest the protective influence of statin use against breast cancer related mortality in agreement with previous Scandinavian studies, although less so with studies in other populations.
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