Pastori D, Pani A, Di Rocco A, et al. - Among non-alcoholic fatty liver disease (NAFLD) patients treated or not with statins, disparities in liver function tests, including alanine transaminase aminotransferase (ALT), aspartate transaminase (AST), and gamma-glutamyl transpeptidase (GGT) were explored herein. This analysis involved 22 studies with 2,345 NAFLD patients. Findings of the interventional studies revealed that statin treatment resulted in decrease in ALT, AST and GGT with a percentage mean difference of -35.41%, -31.78% and -25.57%, respectively, while outcomes from observational studies demonstrated a null impact indicating a liver safety in NAFLD patients.