Vella V, Galgani I, Polito L, et al. - In view of the variation in frequency of recurrences in Staphylococcus aureus skin and soft tissue infections (SA-SSTI) recurrences even after successful initial treatment and the significance of determining their exact burden and timing of recurrent disease for planning and evaluating interventions to prevent recurrent SSTI, researchers conducted this retrospective study analyzing 4,755 SSTI cases reported at Columbia, 2,873 at Chicago, and 6,433 at Vanderbilt according to a biennial cohort design. S. aureus was confirmed to be the etiologic factor in 452, 153, and 354 cases, respectively. Per observations, healthy adults commonly exhibit SA-SSTI recurrences. At least 1 in 6 individuals experienced recurrence during the 1 year following the primary event.