Cindolo L, et al. - The objective herein was to compare the efficacy, safety, Patient Global Impression of Improvement (PGI-I), and complications rates after 180-W GreenLight laser (180-W GL laser) standard and anatomical photoselective vaporization (sPVP and aPVP), in patients with benign prostatic hyperplasia (BPH). Similar functional results and complication rates were illustrated after aPVP and sPVP. Nonetheless, it was noted that aPVP was used in larger prostates. High patient’s satisfaction was guaranteed via both techniques.

Methods

• Patients, who underwent sPVP or aPVP to relief BPH symptoms, were selected from a multi-institutional database.
• An estimation was conducted of the IPSS, Qmax, and prostate-specific antigen (PSA), at baseline and during the follow-up.
• PGI-I score along with early and late complications were recorded at follow-up visits.
• In order to compute the effect of aPVP vs. sPVP on PGI-I and on early and late complication rates, before and after adjustment for propensity score, log-binomial and multivariable proportional odds regression models were fitted.

Results

• Researchers enrolled 813 patients.
• Herein, 50.4% patients underwent aPVP.
• Those who underwent aPVP illustrated larger prostate (64 vs. 55 mL, p < 0.001) and higher baseline PSA levels (3.1 vs. 2.5 ng/mL, p < 0.001).
• PGI-I score signaled as very improved, improved, slightly improved, unchanged, or worsened in 55.5, 32.8, 8.3, 2.3, and 1.2% of the cases, respectively.
• No variations were reported based on the technique used (p=0.420).
• Occurrence of acute urinary retention was noted in 9.2 vs. 8.9% of patients after aPVP vs. sPVP (p=0.872).
• Failure to identify variations in: Patients’ satisfaction (OR 1.19, p=0.256), early complications (RR 0.93, p=0.387), early urge/incontinence symptoms (RR 0.97, p=0.814), and late complications rates (RR 0.70, p=0.053), after aPVP vs. sPVP, in all models.