Cui K, Lyu S, Liu H, et al. - Researchers investigated how long-term results following staged complete revascularization vs after culprit-only percutaneous coronary intervention (PCI) are influenced by diabetes status. This study included 371 diabetic patients (staged PCI: 164, culprit-only PCI: 207) and 834 nondiabetic patients (staged PCI: 412, culprit-only PCI: 422) with ST-segment elevation myocardial infarction (STEMI) and multivessel disease. The five-year major adverse cardiac and cerebrovascular event was considered as the primary endpoint. Findings revealed that diabetes did not independently predict adverse cardiovascular events at 5 years in patients with STEMI and multivessel disease. In addition, the superiority of an approach of staged complete revascularization over culprit-only PCI was demonstrated in nondiabetic patients, whereas the benefit of staged PCI was found to be attenuated in diabetic patients.