Russell J, et al. - Researchers conducted this analysis including a sample of lung cancer patients (n=145) who were receiving chemotherapy to evaluate the differences in the number and types of symptom clusters at three time points [ie, before their next cycle of chemotherapy (CTX), the week after CTX, and two weeks after CTX] using ratings of symptom occurrence and severity and to evaluate for changes in these symptom clusters over time. Across the two symptom dimensions (ie, occurrence and severity) and the three assessments, they identified 6 distinct symptom clusters. However, there were only three of these clusters that were relatively stable across both dimensions and across time (ie, lung cancer specific, psychological, nutritional). They identified 2 additional clusters that varied by time but not by symptom dimension (ie, epithelial/gastrointestinal, epithelial). Using only the severity dimension, a sickness behavior cluster was identified at each assessment with the exception of the week before CTX. Within each cluster, most common symptoms seem relatively stable across the two dimensions, as well as across time.