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Stability across time of the neutrophil-lymphocyte and lymphocyte-neutrophil ratios and associations with outcomes in cardiac surgery patients

Journal of Cardiothoracic Surgery Sep 20, 2019

Green J, et al. - Among 558 patients who underwent coronary artery bypass grafts and/or valve surgery, researchers assessed the temporal stability as well as prognostic significance of the preoperative Neutrophil-to-Lymphocyte ratio (NLR) and Lymphocyte-to-Neutrophil ratio (LNR) in this retrospective review. Patients with immunosuppressed status were removed from the study. According to the median value of preoperative NLR, they classified patients into high NLR and low NLR groups. Findings revealed the stability of both NLR and LNR over time, up to 100 days. LNR values vs NLR were more consistent. A significant link of high LNR with a reduced risk of mid-term mortality was identified. Compared with NLR, LNR displayed a stronger link with mid-term mortality. Overall, a possible greater utility of LNR, as well as its clinical value as a marker, was indicated.
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