Weissbart SJ, et al. - Authors aimed to compare the brain activity during urgency before and after sacral neuromodulation in women with overactive bladder and according to response to treatment. They noted that after successful sacral neuromodulation brain activity during urgency changes. In women who underwent successful treatment, pretreatment brain activity levels in the bilateral anterior cingulate cortex, right insula, bilateral dorsolateral prefrontal cortex, right orbitofrontal cortex, right supplementary motor area, and right sensorimotor cortex were higher. Findings suggested that in women with higher levels of pretreatment brain activity during urgency, sacral neuromodulation could be more effective.