Xiong A, Li C, Xu J, et al. - Researchers analyzed 237 stage I-III lung adenocarcinoma patients with epidermal growth factor receptor mutation following surgery to determine the prognostic significance of solid pattern for bone metastases (BM) in this patient population. The participants were split into four categories: solid-present cases with BM, solid-absent cases with BM, solid-present cases without BM, and solid-absent cases without BM. Shorter disease-free survival (DFS) (15 months vs 19 months) and overall survival (OS) ((47 months vs 77 months) were seen in patients with a solid pattern. Significantly shorter bone disease-free survival was observed in solid-present patients vs solid-absent patients. These data indicated that solid pattern was a predictor of worse DFS as well as OS and also demonstrated shortened interval between surgery and BM.