Kimble MM, et al. - In a large urban health system in Los Angeles, CA, patients newly identified as hepatitis C virus (HCV) antibody positive were examined for the frequency of HCV clearance and for the correlates of viral clearance. This study included 320 patients, and of these, 56% were male. The single largest age group (62%) was of baby boomers (52–72 years of age). Spontaneous HCV clearance was reported in 58% (n = 185). Women vs men showed slightly higher HCV viral clearance (63% vs 53%). Blacks/African Americans vs whites showed clearance of 37% vs 58%. A greater frequency of HCV spontaneous clearance was confirmed in this study. This study also identified certain subgroups as more likely to clear HCV infection, and African Americans and patients with chronic kidney disease are at a higher risk for HCV infection and need to be prioritized for HCV screening and treatment initiatives.