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Smoking is associated with higher disease activity in rheumatoid arthritis: A longitudinal study controlling for time-varying covariates

The Journal of Rheumatology Apr 04, 2019

Gianfrancesco MA, et al. - Using electronic health record data from 2013 to 2017, researchers examined 282 cases with rheumatoid arthritis (RA) to study the relationship between smoking and RA outcomes. They noted an association of smoking with an increase of 0.64 units in the patient global score vs nonsmoking. A relationship between smoking and 2.58 more swollen joints was also reported. They found no statistically significant difference when smoking was correlated with greater clinical disease activity score (2.11). No association between smoking and physician global score or C-reactive protein levels was noted. They observed an inverse relationship between smoking and tender joint count.

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