Loreto AR, et al. - Smoking treatment effectiveness and retention were investigated in a population with and without mental disorders (MD). In samples with high rates of medical, psychiatric, and addiction disorders, the physicians supported the use of cognitive behavioral therapy (CBT) plus nicotine patch plus bupropion as well as CBT plus nicotine patch plus gum. These findings supported those of previous studies in the general population. Based on cognitive-behavioral concepts, pharmacological treatment correlated with group CBT, and combined with ongoing MD treatment seemed to be the best option for smoking cessation treatment among patients with MD. Units that deal with patients with MD, like CAPS in Brazil, needed to be encouraged to treat smoking addiction in this population. Future studies ought to examine retention rates in other samples of patients with MD.