Small-vessel PCI outcomes in men, women, and minorities following platinum chromium everolimus-eluting stents: Insights from the pooled PLATINUM Diversity and PROMUS Element Plus Post-Approval studies
Catheterization and Cardiovascular Interventions Jan 27, 2019
Guedeney P, et al. - In a large sample of men, women, and minorities from the PLATINUM Diversity and PROMUS Element Plus stent registries, researchers assessed the 1-year outcomes following platinum chromium everolimus-eluting stents (PtCr-EES) in small vs non-small coronary arteries. The outcomes were risk-adjusted by using multivariable Cox regression. The definition of small-vessel percutaneous coronary intervention (SV-PCI) was ≥1 target lesion with reference vessel diameter (RVD) ≤2.5 mm. A total of 1,607 (39%) patients had small-vessel PCI among 4,155 out of 4,182 (99%) patients with available RVD. Findings revealed no increased major adverse cardiac event or target vessel revascularization in association with SV-PCI with PtCr-EES. In women and minorities vs white men, the observed increased myocardial infarction risk was not attributable to SV-PCI with PtCr-EES.
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