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Small airway oscillometry indices: Repeatability and bronchodilator responsiveness in young children

Pediatric Pulmonology Aug 24, 2017

Knihtilä H et al. – This study evaluated bronchodilator responsiveness (BDR) in healthy children (N = 103; aged 2–7 years) for determining their cutoff values for BDR (R5–20, R5–20%, and area under the reactance curve). Subsequently, repeatability between 2 impulse oscillometry (IOS) measurements in young children (n = 43; aged 4–8 years) with asthmatic symptoms (7–14 days apart) was assessed, including cutoff values for significant between–visit changes. It was concluded that although the evaluated IOS parameters may show greater variability than the conventional IOS indices during follow–up, between–visit agreement remains good. Thus, these IOS indices provide potentially useful endpoints for monitoring lung function in young children.

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