Asahina Y, et al. - As a part of this research, the outcomes of surgical cystotomy were exploratively analyzed for recurrent diabetic cystoid macular edema (CME). A substantial improvement was revealed in the central retinal thickness (CRT), central minimum macular thickness (CMMT), macular volume (MV) and best-corrected visual acuity (BCVA), 6 months following surgical cystectomy. Hence, the findings indicated that intraoperative optical coherence tomography (iOCT)-guided cystotomy could serve as another treatment option for refractory CME in diabetic eyes.