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Sites of synchronous distant metastases, prognosis, and nomogram for small cell lung cancer patients with bone metastasis: A large cohort retrospective study

Journal of Oncology Aug 02, 2021

Fan Z, Huang Z, Tong Y, et al. - Researchers sought to determine the site of synchronous distant metastasis to other organs in small cell lung cancer (SCLC) patients who have developed bone metastasis (BM). They also sought to construct a robust predictive prognostic model. This analysis involved 6253 patients. Age, gender, primary site, radiotherapy, chemotherapy, brain metastasis, liver metastasis, and marital status were discovered as independent prognostic factors for SCLC with BM. The most common organ for extraskeletal metastases was the liver, followed by the lung. The longest mean survival time was noted in cases with only BM. It is expected that the prognostic nomogram proposed herein would afford an accurate as well as personalized instrument for prognosis prediction of SCLC patients with BM. In addition, treatment selection is aided by ascertaining the sites of synchronous extraskeletal metastases as well as the associated prognosis.

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