Single embryo transfer by Day 3 time-lapse selection vs Day 5 conventional morphological selection: A randomized, open-label, non-inferiority trial
Human Reproduction Mar 17, 2018
Yang L, et al. - In this work, researchers investigated if single cleavage-stage (Day 3) embryo transfer using a time-lapse (TL) hierarchical classification model would achieve comparable ongoing pregnancy rates (OPR) to single blastocyst (Day 5) transfer by conventional morphological (CM) selection. They noted that the OPR from Day 3 cleavage-stage single embryo transfer (SET) using hierarchical classification time-lapse selection was markedly lower compared with that from Day 5 blastocyst SET using conventional morphology, however, in women undergoing IVF, it seemed to be clinically acceptable.
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