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Single‐cell immune profiling in coronary artery disease: the role of state‐of‐the‐art immunophenotyping with mass cytometry in the diagnosis of atherosclerosis

Journal of the American Heart Association Dec 14, 2020

Kott KA, Vernon ST, Hansen T, et al. - This study was sought to examine some of the highlights of the important developments in cardioimmunology and summarizes the clinical evidence linking the immune system and atherosclerosis. In the world, coronary artery disease remains the leading cause of death globally and is a major burden to every health system. There were significant improvements in risk modification, treatments, and mortality; nevertheless, the ability to diagnose asymptomatic disease for early intervention remains limited. The findings demonstrated that current discoveries regarding the inflammatory nature of atherosclerosis have prompted evaluation into new methods of diagnosis and treatment of coronary artery disease.

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