Fritz J, et al. – In this prospective study, researchers evaluated the signal–to–noise ratio (SNR) and contrast–to–noise ratio (CNR) of integrated parallel acquisition technique (PAT) and simultaneous multislice (SMS) acceleration and various combinations thereof, and they further compared two 4–fold–accelerated (PAT2–SMS2) high–resolution turbo spin echo (TSE) magnetic resonance imaging (MRI) protocols of the knee against a clinical 2–fold–accelerated (PAT2–SMS1) TSE standard. They illustrate the signal preservation capabilities of SMS over PAT acceleration, which allow for similar SNR and CNR of 4–fold PAT2–SMS2 and 2–fold PAT2–SMS1 acceleration. It was indicated that four–fold–accelerated TSE through the combination of PAT2 and SMS2 enables approximately 50% shorter acquisition times compared with regular PAT2 acceleration, similar quantitative and qualitative image quality, and holds promise for a meaningful increase of the efficiency of clinical 2–dimensional MRI of the knee.