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Simultaneous induction of HSP70 expression, and degranulation, in IgE/Ag-stimulated or extracellular HSP70-stimulated mast cells (129/200)

Allergy Sep 08, 2017

Li X, et al. - Researchers undertook this study to report the induction of HSP70 expression during antigen stimulation in mast cells. It was noted that FcεRI stimulation in bone marrow derived mast cells (BMMC) and basophils induces HSP70 expression and its release. In addition, extracellular HSP70 induces degranulation and mediator release via phosphorylation of LAT.
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