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Similar subclinical enthesitis in celiac and inflammatory bowel diseases by ultrasound suggests a gut enthesis axis independent of spondyloarthropathy spectrum

Rheumatology May 25, 2018

Ureyen SB, et al. - Researchers compared inflammatory bowel diseases (IBD) and celiac disease for enthesitis on US. In IBD, higher enthesitis scores than celiac disease would support a shared pathogenic mechanism between IBD and spondyloarthritis, whereas a general impact of gut inflammation on the enthesis could be suggested by the similar scores. Findings suggested the similar magnitude of subclinical enthesopathy scores between celiac disease and IBD in comparison with healthy controls (HCs). Abnormal gut permeability, which could be modified by the genetic architecture of IBD leading to clinical arthropathy was the common factor between both diseases and enthesopathy.
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