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sIL-24 peptide, a human interleukin-24 isoform, induces mitochondrial-mediated apoptosis in human cancer cells

Cancer Chemotherapy and Pharmacology Sep 04, 2017

Valiyari S, et al. – Researchers undertook an investigation and examined the cytotoxic properties of a recombinant smallest isoform of interleukin-24 (IL-24) (sIL–24) and the underlying molecular mechanisms in PC–3, A549, U937, and Raji cancer cells as well as normal cell line MRC–5. For potential treatment of human cancers, the sIL–24 peptide outlined as a promising candidate.
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