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Significance of serum FGF-23 for risk assessment of contrast-associated acute kidney injury and clinical outcomes in patients undergoing coronary angiography

PLoS Neglected Tropical Diseases Jul 29, 2021

Huang SS, Huang PH, Leu HB, et al. - Researchers sought to determine if increased fibroblast growth factor (FGF)-23 levels are related to an elevated risk for contrast-associated acute kidney injury (CA-AKI) as well as major adverse cardiovascular events (MACE) in patients (n = 492) receiving coronary angiography. A total of 41 (8.3%) patients developed CA-AKI. Findings revealed that an elevated risk for CA-AKI and future MACE was observed in relation to elevated FGF-23 levels in patients undergoing coronary angiography. A likely role of FGF-23 was suggested not only in early diagnosis of CA-AKI but also in predicting clinical results following coronary angiography.

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