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Significance of pancreatic calcification on preoperative computed tomography of intraductal papillary mucinous neoplasms

Journal of Gastroenterology and Hepatology Nov 01, 2019

Tsujimae M, Masuda A, Shiomi H, et al. - Researchers examined whether pancreatic calcification, a characteristic of chronic pancreatitis, is associated with invasive intraductal papillary mucinous neoplasm (IPMN). In this study, 157 patients who underwent resection for IPMN between April 2001 and October 2016 were included (intraductal papillary mucinous adenoma, n = 76; noninvasive intraductal papillary mucinous carcinoma [IPMC], n = 32; and invasive IPMC, n = 49). Pancreatic calcification was identified in 17.2% (27/157) of the resected IPMN on preoperative CT. As per the univariate analyses, pancreatic calcification was observed in significant association with jaundice, high serum carbohydrate antigen 19-9 levels, and invasive IPMC. An association between pancreatic calcification on CT and invasive IPMC was identified. Findings suggest a possible predictive value of pancreatic calcification for invasive IPMC.
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