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Significance of overall concurrent chemoradiotherapy duration on survival outcomes of stage IIIB/C non-small-cell lung carcinoma patients: Analysis of 956 patients

PLoS Neglected Tropical Diseases Jul 25, 2019

Topkan E, et al. - Researchers examined survival in relation to prolonged overall radiotherapy duration (ORTD) among 956 patients who underwent concurrent chemoradiotherapy for stage IIIB/C non-small-cell lung cancers. This retrospective but largest-to-date single institutional cohort analysis revealed significantly poorer overall survival, locoregional progression-free survival and progression-free survival outcomes in correlation to longer ORTD beyond ≥50 days, where reduced locoregional control rates appeared to be the main causative.
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