Lang BHH, et al. - Experts scrutinized the connection between the appearance of hyperechoic marks (HEMs) during high-intensity focused ultrasound (HIFU) ablation of benign thyroid nodules and nodule shrinkage at 6 months. This study was conducted on 136 patients who underwent HIFU for benign thyroid nodule. They reported that lower BMI and greater applied power increase chance of hyperechoic marks. Findings revealed that the appearance of HEMs during treatment was an independent determinant of treatment success following single-session HIFU ablation of benign thyroid nodule.