Rosenstock P, et al. – Experts compared the expression of Siglecs–7, –9 and –10 on natural killer cells (NK cells) from normal weight and obese subjects. Findings of this study suggested the reduction of Siglec–7 expression on CD56bright NK cells as a marker for their dysfunction. On the NK cell lines, NK–92 and NKL, Siglecs–7, –9 and –10 were not expressed. When comparing the two NK cell subpopulations CD56bright and CD56dim, they revealed the higher amount of sialic acids on the surface of CD56bright NK cells compared to CD56dim NK cells regardless of body weight.