Sahak H, Saqalain M, Lott P, et al. - In the present study, the researchers sought to examine the prevalence of sickle cell maculopathy (SCM), associations with age, gender, genotype and proliferative sickle cell retinopathy (PSR) stage and the impact on visual acuity. For a consecutive series of 74 adults with sickle cell disease, age, gender and visual acuity were reported and spectral-domain OCT and ultra-widefield images of the macula and retina were analyzed. A common finding in the eyes of adults with sickle cell disease is SCM. For both genotypes of HbSS and HbSC, the prevalence is identical and is not related to the PSR stage. Typically, high-contrast distance visual acuity is preserved.