Short-term weight change and live birth among women with unexplained infertility and polycystic ovary syndrome undergoing ovulation induction
Fertility and Sterility Oct 09, 2020
Vitek W, Sun F, Hoeger KM, et al. - In this secondary analysis of randomized trials, experts aspired to explore whether short-term weight change among women with unexplained infertility (UI) and polycystic ovary syndrome (PCOS) undergoing ovulation induction is correlated with live birth. The sample consisted of 900 women with UI and 750 women with PCOS. For 856 women with UI and 697 women with PCOS, weight data were available. Among women with PCOS and ≥3 kg weight gain and women with PCOS who did not gain weight, there was no difference in the live birth rate. Regardless of the medication received, women with PCOS gained an average of 2.2 kg, while women with UI experienced no short-term weight change during ovulation induction. Live birth rates were not associated with weight gain in women with PCOS.
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