Short-term progression of cardiometabolic risk factors in relation to age at type 2 diabetes diagnosis: A longitudinal observational study of 100,606 individuals from the Swedish National Diabetes Register
Diabetologia - Clinical and Experimental Diabetes and Metabolism Feb 10, 2018
Steinarsson AO, et al. - This longitudinal observational study was performed to assess the clinical characteristics at type 2 diabetes diagnosis and the broad trajectories in cardiometabolic risk factors over the initial years following diagnosis in relation to age at diagnosis. Compared with individuals who develop diabetes later in life, those who developed type 2 diabetes at a younger age were more often obese, showed a more adverse lipid profile, had higher HbA1c and a faster deterioration in glycaemic control. These differences largely remained for several years after diagnosis. Thus, findings supported the notion that early-onset type 2 diabetes could be a more pathogenic condition than the late-onset disease.
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