Harris L, et al. - This meta-analysis integrates the available evidence on the impact of short-term periods of intermittent energy restriction (weekly intermittent energy restriction; ≥7-d energy restriction) in the treatment of overweight and obesity among adults in comparison with usual care (daily continuous energy restriction). For the treatment of obesity, this systematic review supports the use of weekly intermittent energy restriction as an alternative option. At present, there is insufficient evidence to support the long-term sustainable effects of weekly intermittent energy restriction on weight management.