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Short and long‐term outcomes of chronic pulmonary hypertension in preterm infants managed using a standardized algorithm

Pediatric Pulmonology Dec 07, 2020

Baczynski M, Kelly E, McNamara PJ, et al. - Although there is insufficient evidence on management strategies for chronic pulmonary hypertension (cPH) in chronic lung disease (CLD) of prematurity, researchers conducted this retrospective cohort study to assess clinical outcomes following a standardized policy, wherein only cPH with right‐ventricular (RV) dilatation was treated and diuretics were used as first‐line therapy; cPH without RV‐dilatation was managed expectantly. All infants with CLD were classified as “CLD‐only” or “CLD‐cPH”, utilizing echocardiography at ≥ 36 weeks postmenstrual age. Using RV-dilatation as a therapeutic threshold, primary treatment of CLD-cPH with diuretics will lead to symptomatic improvement, disease stabilization, and post-discharge results comparable to infants without cPH.

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