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Short and long‐term outcomes of chronic pulmonary hypertension in preterm infants managed using a standardized algorithm

Pediatric Pulmonology Dec 17, 2020

Baczynski M, Kelly E, McNamara PJ, et al. - Since there exists limited data about treatment strategies for chronic pulmonary hypertension (cPH) in chronic lung disease (CLD) of prematurity, therefore, researchers undertook this retrospective cohort analysis to assess clinical results after a standardized policy, in which only cPH with right‐ventricular (RV) dilatation was treated and diuretics were used as first‐line treatment; cPH without RV‐dilatation was treated expectantly. Experts grouped all infants with CLD as “CLD‐only” or “CLD–cPH,” employing echocardiography at ≥ 36 weeks postmenstrual age. They conducted intergroup comparison. According to findings, use of diuretics in the primary management of CLD–cPH, using RV‐dilatation as therapeutic threshold, may lead to symptomatic improvement, disease stabilization as well as post‐discharge results comparable to infants without cPH.

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