Mbeye NM, et al. - An appraisal was performed of the effectiveness of shifting tasks from pharmacy to non-pharmacy personnel for providing antiretroviral therapy (ART), to people living with HIV, in low-income and middle-income countries. The low certainty of the evidence implied a greater tendency that additional studies could detect the effects of the intervention to be substantially different from the yielded data. If resource-constrained countries decided to undertake this shift, this ought to be accompanied by robust monitoring and impact evaluation.