Shear wave elastography as a quantitative biomarker of clinically significant portal hypertension: A systematic review and meta-analysis
American Journal of Roentgenology | Apr 02, 2018
Suh CH, et al. - In order to qualify shear wave elastography (SWE) as a biomarker for clinically significant portal hypertension (CSPH), authors conducted this systematic review and meta-analysis. It was observed that the diagnostic performance of SWE for the diagnosis of CSPH was fairly good, displaying a summary sensitivity of 85% and summary specificity of 85%. Yielded data supported the value of SWE as a diagnostic biomarker for CSPH. Despite significant heterogeneity in the imaging devices, protocols, liver stiffness measurement methods, and cutoff values used, evidence favoring SWE as a biomarker for CSPH ought to be taken into account in the biomarker qualification process and management of patients with CSPH.
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