Sex-specific role of estimated aortic pulse wave velocity in the prediction of future thoracic aortic aneurysm expansion
Canadian Journal of Cardiology Feb 03, 2021
Boczar KE, Boodhwani M, Beauchesne L, et al. - Because it is possible to mathematically estimate aortic pulse wave velocity (e-aPWV), researchers assessed gender-specific impacts of e-aPWV on thoracic aortic aneurysm (TAA) expansion. Recruitment of 105 patients with TAA was done. Using validated equations based on age and MAP, experts estimated e-aPWV. They tested sex*eaPWV interaction. Of participants, 78% were males. In both men and women, TAA expansion was best predicted by e-aPWV. Findings revealed an independent association of e-aPWV with future TAA expansion, and this link was identified to be strongest in females. e-aPWV was recognized as an instrument that is simple and free of cost and not only enables improved TAA risk stratification but also demonstrates significant potential to improve the care of individuals (especially women) with TAA.
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