Gul B, et al. - In patients with acute myocardial infarction (AMI), this patient level pooled analysis examined sex-based and regional outcomes after contemporary percutaneous coronary intervention (PCI) with the Xience V stent. They enrolled 1,938 patients treated with Xience V stents in the setting of AMI. Compared to men, women with AMI who underwent PCI with XIENCE DES had higher all-cause mortality at one year. Results also showed increased major adverse cardiac events (MACE) among US patients vs the patients from China and Japan. Findings revealed that major bleeding, rather than female sex, forecast the higher observed all-cause mortality, after adjusting for differences in demographics.