Ford TJ, Khan A, Docherty KF, et al. - Researchers assessed gender disparities in procedural net adverse clinical events as well as long-term results after rotational atherectomy (RA). They observed 765 consecutive patients receiving RA percutaneous coronary intervention for a median duration of 4.7 years. They noted that the receipt of radial procedures was fewer and that of intravascular imaging guidance was less among females. A more frequent occurrence of the primary endpoint of net adverse cardiac events (net adverse clinical events: all-cause mortality, myocardial infarction, stroke, target vessel revascularization plus any procedural complication) was reported, following propensity score adjustment, among female patients, and the driver of this was a raised risk of procedural complications rather than procedural major adverse cardiac events. As per the findings, a greater risk of procedural complications post-rotational atherectomy may be seen in women. These incorporate periprocedural bleeding episodes and coronary perforation resulting in cardiac tamponade. Despite this, males and females demonstrated similar adjusted overall long-term survival free of major adverse cardiac events.